abstract：:A comparison of mitochondrial DNA sequences was undertaken for two genes among orangutans from Borneo and Sumatra. The distribution of haplotypes among 42 individuals for NADH dehydrogenease subunit 3 and 39 individuals for cytochrome B was used to infer population structure. The haplotypes among all Bornean orangutan...

journal_title：Journal of molecular evolution

authors： Muir CC,Galdikas BM,Beckenbach AT

更新日期：2000-11-01 00:00:00

abstract：:Photosynthetic eukaryotes can, according to features of their chloroplasts, be divided into two major groups: the red and the green lineage of plastid evolution. To extend the knowledge about the evolution of the red lineage we have sequenced and analyzed the chloroplast genome (cp-genome) of Cyanidium caldarium RK1, ...

journal_title：Journal of molecular evolution

authors： Glöckner G,Rosenthal A,Valentin K

更新日期：2000-10-01 00:00:00

abstract：:Short interspersed DNA elements (SINEs) amplify by retroposition either by (i) successive waves of amplification from one or a few evolving master genes or by (ii) the generation of new master genes that coexist with their progenitors. Individual, highly conserved, elements of the B1 SINE family were identified from t...

journal_title：Journal of molecular evolution

authors： Kass DH,Raynor ME,Williams TM

更新日期：2000-09-01 00:00:00

abstract：:Calmodulin is a calcium-binding EF-hand protein that is an activator of many enzymes as well as ion pumps and channels. Due to its multiple targets and its central role in the cell, understanding the evolutionary history of calmodulin genes should provide insights into the origin of genetic complexity in eukaryotes. W...

journal_title：Journal of molecular evolution

authors： Karabinos A,Bhattacharya D

更新日期：2000-08-01 00:00:00

abstract：:Complete chloroplast 23S rRNA and psbA genes from five peridinin-containing dinoflagellates (Heterocapsa pygmaea, Heterocapsa niei, Heterocapsa rotun-data, Amphidinium carterae, and Protoceratium reticulatum) were amplified by PCR and sequenced; partial sequences were obtained from Thoracosphaera heimii and Scrippsiel...

journal_title：Journal of molecular evolution

authors： Zhang Z,Green BR,Cavalier-Smith T

更新日期：2000-07-01 00:00:00

abstract：:The sequence of a cloned Anopheles stephensi gene showed 72% inferred amino acid identity with Drosophila melanogaster Dox-A2 and 93% with its putative ortholog in Anopheles gambiae. Dox-A2 is the reported but herein disputed structural locus for diphenol oxidase A2. Database searches identified Dox-A2 related gene se...

journal_title：Journal of molecular evolution

authors： Garvey CF,Malcolm CA

更新日期：2000-06-01 00:00:00

abstract：:Previous studies have shown that pituitary growth hormone displays an episodic pattern of evolution, with a slow underlying evolutionary rate and occasional sustained bursts of rapid change. The present study establishes that pituitary prolactin shows a similar pattern. During much of tetrapod evolution the sequence o...

journal_title：Journal of molecular evolution

authors： Wallis M

更新日期：2000-05-01 00:00:00

abstract：:We have previously shown that several multicopy gene families within the major histocompatibility complex (MHC) arose from a process of segmental duplication. It has also been observed that retroelements play a role in generating diversity within these duplicated segments. The objective of this study was to compare th...

journal_title：Journal of molecular evolution

authors： Freitas EM,Gaudieri S,Zhang WJ,Kulski JK,van Bockxmeer FM,Christiansen FT,Dawkins RL

更新日期：2000-04-01 00:00:00

abstract：:In bacteria, synonymous codon usage can be considerably affected by base composition at neighboring sites. Such context-dependent biases may be caused by either selection against specific nucleotide motifs or context-dependent mutation biases. Here we consider the evolutionary conservation of context-dependent codon b...

journal_title：Journal of molecular evolution

authors： McVean GA,Hurst GD

更新日期：2000-03-01 00:00:00

abstract：:Phylogenetic hypotheses of muscle actin evolution are significantly different when a sea urchin is used as a representative echinoderm than when a sea star is used. While sea urchin muscle actins support an echinoderm-chordate sister relationship, sea star sequences suggest that echinoderm muscle actins are convergent...

journal_title：Journal of molecular evolution

authors： White ME,Crother BI

更新日期：2000-02-01 00:00:00

abstract：:To understand the process and mechanism of protein evolution, it is important to know what types of amino acid substitutions are more likely to be under selection and what types are mostly neutral. An amino acid substitution can be classified as either conservative or radical, depending on whether it involves a change...

journal_title：Journal of molecular evolution

authors： Zhang J

更新日期：2000-01-01 00:00:00

abstract：:Long amino acid repeats are often observed in eukaryotic proteins. In humans, several neurological disorders are caused by proteins containing abnormally long polyglutamines. However, no systematic analysis has attempted to investigate the relationship between reiterations of particular amino acids and protein functio...

journal_title：Journal of molecular evolution

authors： Mar Albà M,Santibáñez-Koref MF,Hancock JM

更新日期：1999-12-01 00:00:00

abstract：:In this work detailed statistics on ancestral gene duplication and gene conservation in completely sequenced cellular genomes are presented. Analysis of open reading frame (ORF) products having simultaneous matches in several distinct organisms showed a significant correlation between duplication and conservation. Sys...

journal_title：Journal of molecular evolution

authors： Tekaia F,Dujon B

更新日期：1999-11-01 00:00:00

abstract：:We suggest a nucleotide substitution model that takes correlation between base-paired nucleotides into account. The model includes the estimation of the transition-transversion ratio and allows inference of the shape parameter of a discrete gamma distribution to include rate heterogeneity. A Cox-test statistic, applie...

journal_title：Journal of molecular evolution

authors： Schöniger M,von Haeseler A

更新日期：1999-11-01 00:00:00

abstract：:The heterotrophic theory of the origin of life is the only proposal available with experimental support. This comes from the ease of prebiotic synthesis under strongly reducing conditions. The prebiotic synthesis of organic compounds by reduction of CO(2) to monomers used by the first organisms would also be considere...

journal_title：Journal of molecular evolution

authors： Lazcano A,Miller SL

更新日期：1999-10-01 00:00:00

abstract：:The helix-turn-helix domain-containing family of transcriptional regulators is of ancient origin and has been incorporated into numerous disparate biological processes. As a consequence, the forces shaping its early evolution have been difficult to reconstruct. Herein, we analyze this large and diverse family with a c...

journal_title：Journal of molecular evolution

authors： Rosinski JA,Atchley WR

更新日期：1999-09-01 00:00:00

abstract：:It has recently been argued that living metazoans diverged over 800 million years ago, based on evidence from 22 nuclear genes for such a deep divergence between vertebrates and arthropods (Gu 1998). Two "internal" calibration points were used. However, only one fossil divergence date (the mammal-bird split) was direc...

journal_title：Journal of molecular evolution

authors： Lee MS

更新日期：1999-09-01 00:00:00

abstract：:Computer analyses of various genome sequences revealed the existence of certain periodical patterns of adenine-adenine dinucleotides (ApA). For each genome sequence of 13 eubacteria, 3 archaebacteria, 10 eukaryotes, 60 mitochondria, and 9 chloroplasts, we counted frequencies of ApA dinucleotides at each downstream pos...

journal_title：Journal of molecular evolution

authors： Tomita M,Wada M,Kawashima Y

更新日期：1999-08-01 00:00:00

abstract：:A cDNA encoding a new member of the gene family of major royal jelly proteins (MRJPs) from the honeybee, Apis mellifera, was isolated and sequenced. Royal jelly (RJ) is a secretion of the cephalic glands of nurse bees. The origin and biological function of the protein component (12.5%, w/w) of RJ is unknown. We show t...

journal_title：Journal of molecular evolution

authors： Albert S,Bhattacharya D,Klaudiny J,Schmitzová J,Simúth J

更新日期：1999-08-01 00:00:00

abstract：:Darwinian theory requires that mutations be produced in a nonanticipatory manner; it is nonetheless consistent to suggest that mutations that have repeatedly led to nonviable phenotypes would be introduced less frequently than others-if under appropriate genetic control. Immunoglobulins produced during infection acqui...

journal_title：Journal of molecular evolution

authors： Cowell LG,Kim HJ,Humaljoki T,Berek C,Kepler TB

更新日期：1999-07-01 00:00:00

abstract：:The beta-globin gene cluster of Wistar rat was extensively cloned and the embryonic genes were mapped and sequenced. Four overlapping lambda Dash recombinant clones cover about 31 kb and contain four nonadult beta-globin genes, 5'-epsilon1-gamma1-gamma2-psigamma3-3'. The epsilon1 and gamma2 are active genes, since the...

journal_title：Journal of molecular evolution

authors： Satoh H,Inokuchi N,Nagae Y,Okazaki T

更新日期：1999-07-01 00:00:00

abstract：:Introns are generally believed to evolve too rapidly and too erratically to be of much use in phylogenetic reconstructions. Few phylogenetically informative intron sequences are available, however, to ascertain the validity of this supposition. In the present study the supposition was tested on the example of the mamm...

journal_title：Journal of molecular evolution

authors： Kupfermann H,Satta Y,Takahata N,Tichy H,Klein J

更新日期：1999-06-01 00:00:00

abstract：:Bacterial family C DNA polymerases (DNA pol IIIs), the major chromosomal replicative enzymes, have been provisionally classified based on primary sequences and domain structures into three classes: class I (Escherichia coli DNA pol C-type), class II (Bacillus subtilis DNA pol C-type), and class III (cyanobacterial DNA...

journal_title：Journal of molecular evolution

authors： Huang YP,Ito J

更新日期：1999-06-01 00:00:00

abstract：:A 2550-bp portion of the mitochondrial genome of a Demosponge, genus Tetilla, was amplified from whole genomic DNA extract and sequenced. The sequence was found to code for the 3' end of the 16S rRNA gene, cytochrome c oxidase subunit II, a lysine tRNA, ATPase subunit 8, and a 5' portion of ATPase subunit 6. The Porif...

journal_title：Journal of molecular evolution

authors： Watkins RF,Beckenbach AT

更新日期：1999-05-01 00:00:00

abstract：:The amino acid sequences of 22 alpha-amylases from family 13 of glycosyl hydrolases were analyzed with the aim of revealing the evolutionary relationships between the archaeal alpha-amylases and their eubacterial and eukaryotic counterparts. Two evolutionary distance trees were constructed: (i) the first one based on ...

journal_title：Journal of molecular evolution

authors： Janecek S,Lévêque E,Belarbi A,Haye B

更新日期：1999-04-01 00:00:00

abstract：:The observed and expected frequencies of occurrence of microsatellites in the yeast Saccharomyces cerevisiae were investigated. In all cases, the observed frequencies exceeded the expected ones. In contrast to predictions by Messier et al. (1996), there is no critical number of repeats beyond which the observed freque...

journal_title：Journal of molecular evolution

authors： Pupko T,Graur D

更新日期：1999-03-01 00:00:00

abstract：:Multiple phospholipase A2 (PLA2) isoenzymes found in a single snake venom induce a variety of pharmacological effects. These multiple forms are formed by gene duplication and accelerated evolution of exons. We examined the amino acid sequences of 127 snake venom PLA2 enzymes and their homologues to study in which loca...

journal_title：Journal of molecular evolution

authors： Kini RM,Chan YM

更新日期：1999-02-01 00:00:00

abstract：:The frequencies of ATG triplets in the genomes of various species were systematically analyzed, and the frequency of ATG triplets was significantly low around start codons in both prokaryotic and eukaryotic genomes. In eukaryotes, however, the frequency decrease before the start codon is much more evident than that af...

journal_title：Journal of molecular evolution

authors： Saito R,Tomita M

更新日期：1999-02-01 00:00:00

abstract：:A model of nucleotide substitution that allows the transition/transversion rate bias to vary across sites was constructed. We examined the fit of this model using likelihood-ratio tests by analyzing 13 protein coding genes and 1 pseudogene. Likelihood-ratio testing indicated that a model that allows variation in the t...

journal_title：Journal of molecular evolution

authors： Huelsenbeck JP,Nielsen R

更新日期：1999-01-01 00:00:00

abstract：:Parsimony is commonly used to infer the direction of substitution and mutation. However, it is known that parsimony is biased when the base composition of the DNA sequence is skewed. Here I quantify this effect for several simple cases. The analysis demonstrates that parsimony can be misleading even when levels of seq...

journal_title：Journal of molecular evolution

authors： Eyre-Walker A

更新日期：1998-12-01 00:00:00

abstract：:Minerals may have played a significant role in chemical evolution. In the course of investigating the chemistry of phosphonoacetaldehyde (PAL), an analogue of glycolaldehyde phosphate, we have observed a striking case of catalysis by the layered hydroxide mineral hydrotalcite ([Mg2Al(OH)6][Cl.nH2O]). In neutral or mod...

journal_title：Journal of molecular evolution

authors： De Graaf RM,Visscher J,Xu Y,Arrhenius G,Schwartz AW

更新日期：1998-11-01 00:00:00

abstract：:Phylogenetic relationships of nematodes, nematomorphs, kinorhynchs, priapulids, and some other major groups of invertebrates were studied by 18S rRNA gene sequencing. Kinorhynchs and priapulids form the monophyletic Cephalorhyncha clade that is the closest to the coelomate animals. When phylogenetic trees were generat...

journal_title：Journal of molecular evolution

authors： Aleshin VV,Milyutina IA,Kedrova OS,Vladychenskaya NS,Petrov NB

更新日期：1998-11-01 00:00:00

abstract：:The entire mitochondrial DNA control region (mtDNA D-loop) was sequenced in the seven extant species of Alectoris partridges. The D-loop length is very conserved (1155 +/- 2 nucleotides), and substitution rates are lower than for the mitochondrial cytochrome b gene of the same species, on average. Comparative analyses...

journal_title：Journal of molecular evolution

authors： Randi E,Lucchini V

更新日期：1998-10-01 00:00:00

abstract：:Statistical and biochemical studies of the genetic code have found evidence of nonrandom patterns in the distribution of codon assignments. It has, for example, been shown that the code minimizes the effects of point mutation or mistranslation: erroneous codons are either synonymous or code for an amino acid with chem...

journal_title：Journal of molecular evolution

authors： Freeland SJ,Hurst LD

更新日期：1998-09-01 00:00:00

abstract：:Androgen effects mediated by the androgen receptor (AR) are essential for male reproductive development and virilization. Comparison of AR DNA coding sequence from five primate species, Homo sapiens (human), Pan troglodytes (chimpanzee), Papio hamadryas (baboon), Macaca fascicularis (macaque), and Eulemur fulvus colla...

journal_title：Journal of molecular evolution

authors： Choong CS,Kemppainen JA,Wilson EM

更新日期：1998-09-01 00:00:00

abstract：:Two catalytic functions were required, minimally, for the appearance of DNA in evolution: a ribonucleotide reductase (RNR) and a reverse transcriptase (RT). If one accepts the explanatory strength of the RNA world model, it is clear that DNA molecules arose in the RNA world at some stage during the early evolution of ...

journal_title：Journal of molecular evolution

authors： León PE

更新日期：1998-08-01 00:00:00

abstract：:Drosophilidae is a large, widely distributed family of Diptera including 61 genera, of which Drosophila is the most representative. Drosophila feeding is part of the saprophytic trophic chain, because of its dependence upon decomposing organic matter. Many species have adapted to fermenting fruit feeding or to artific...

journal_title：Journal of molecular evolution

authors： Atrian S,Sánchez-Pulido L,Gonzàlez-Duarte R,Valencia A

更新日期：1998-08-01 00:00:00

abstract：:The evolutionary relationships among arthropod hemocyanins and insect hexamerins were investigated. A multiple sequence alignment of 12 hemocyanin and 31 hexamerin subunits was constructed and used for studying sequence conservation and protein phylogeny. Although hexamerins and hemocyanins belong to a highly divergen...

journal_title：Journal of molecular evolution

authors： Burmester T,Massey HC Jr,Zakharkin SO,Benes H

更新日期：1998-07-01 00:00:00

abstract：:This study was designed to characterize further the nontranscribed intergenic spacers (NTSs) of the 5S rRNA genes of fish and evaluate this marker as a tool for comparative studies. Two members of the closely related North American Great Lakes cisco species complex (Coregonus artedi and C. zenithicus) were chosen for ...

journal_title：Journal of molecular evolution

authors： Sajdak SL,Reed KM,Phillips RB

更新日期：1998-06-01 00:00:00

abstract：:Seven new Italian and two new British HTLV-II isolates were obtained from injecting drug users and the entire long terminal repeat (LTR) region was sequenced. Restriction analysis showed that all the Italian isolates are of the IIb subtype, whereas the British isolates are of the IIa subtype. To understand whether the...

journal_title：Journal of molecular evolution

authors： Salemi M,Vandamme AM,Gradozzi C,Van Laethem K,Cattaneo E,Taylor G,Casoli C,Goubau P,Desmyter J,Bertazzoni U

更新日期：1998-05-01 00:00:00